Petite compilation d’articles sur les Coronavirus et les dichroïsme circulaires JASCO :
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Les articles :
Phosphorylation of the arginine/serine dipeptide‐rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization
2008 / The FEBS Journal
Coronavirus nucleocapsid protein is abundant in infected cells and participates in viral RNA replication and transcription. The central domain of …
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Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
2006 / Viral Research
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is the cause of an atypical pneumonia that affected Asia, North America and Europe …
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The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding
2020 /
Many pathogens take advantage of the dependence of the host on the interaction of hundreds of extracellular proteins with the …
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Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate
2017 / Journal of Pharmaceutical Sciences
From 2002 to 2003, a global pandemic of severe acute respiratory syndrome (SARS) spread to five continents and caused 8,000 …
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Structural and functional characterization of MERS coronavirus papain-like protease
2014 / Journal of Biomedical Science
A new highly pathogenic human coronavirus (CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), has emerged in Jeddah and Saudi Arabia …
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Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins
2016 / Journal of Virology
The fusion peptides (FP) play an essential role in fusion of viral envelope with cellular membranes. The location and properties …
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Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus
2006 / Journal of Structural Biology
The Spike (S) glycoprotein of coronaviruses (CoV) mediates viral entry into host cells. It contains two hydrophobic heptad repeat (HR) regions, denoted HRN and …
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Mutation of Gly-11 on the Dimer Interface Results in the Complete Crystallographic Dimer Dissociation of Severe Acute Respiratory Syndrome Coronavirus 3C-like Protease
2007 / Journal of Biological Chemistry
SARS-CoV 3C-like protease (3CLpro) is an attractive target for anti-severe acute respiratory syndrome (SARS) drug discovery, and its dimerization has …
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Identification and Characterization of the Putative Fusion Peptide of the Severe Acute Respiratory Syndrome-Associated Coronavirus Spike Protein
2005 / Journal of Virology
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a newly identified member of the family Coronaviridae and poses a serious public …
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Structural characterization of the fusion-active complex of severe acute respiratory syndrome (SARS) coronavirus
2004 / PNAS
The causative agent of a recent outbreak of an atypical pneumonia, known as severe acute respiratory syndrome (SARS), has been …
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Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
2014 / Nature Communications
A novel human coronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), has caused outbreaks of a SARS-like illness with high case …
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Severe Acute Respiratory Syndrome Coronavirus nsp9 Dimerization Is Essential for Efficient Viral Growth
2009 / Journal of Virology
The severe acute respiratory syndrome coronavirus (SARS-CoV) devotes a significant portion of its genome to producing nonstructural proteins required for …
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Differential Inhibitory Activities and Stabilisation of DNA Aptamers against the SARS Coronavirus Helicase
2008 / ChemBioChem
The helicase from severe acute respiratory syndrome coronavirus (SARS‐CoV) possesses NTPase, duplex RNA/DNA‐unwinding and RNA‐capping activities that are essential for …
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Structural basis for dimerization and RNA binding of avian infectious bronchitis virus nsp9
2017 / Protein Science
The potential for infection by coronaviruses (CoVs) has become a serious concern with the recent emergence of Middle East respiratory …
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Critical Assessment of Important Regions in the Subunit Association and Catalytic Action of the Severe Acute Respiratory Syndrome Coronavirus Main Protease
2005 / Journal of Biological Chemistry
The severe acute respiratory syndrome (SARS) coronavirus (CoV) main protease represents an attractive target for the development of novel anti-SARS …
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Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors
2004 / Biochemical and Biophysical Research Communications
Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is a newly identified member of Family Coronaviridae. Coronavirus envelope spike protein S is a class I viral fusion …
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The Aromatic Domain of the Coronavirus Class I Viral Fusion Protein Induces Membrane Permeabilization: Putative Role during Viral Entry
2004 / Biochemistry
Coronavirus (CoV) entry is mediated by the viral spike (S) glycoprotein, a class I viral fusion protein. During viral and …
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Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein
2013 / FEBS Letters
The coronavirus (CoV) N protein oligomerizes via its carboxyl terminus. However, the oligomerization mechanism of the C-terminal domains (CTD) of …
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Characterization of the Heptad Repeat Regions, HR1 and HR2, and Design of a Fusion Core Structure Model of the Spike Protein from Severe Acute Respiratory Syndrome (SARS) Coronavirus†
2004 / Biochemistry
Severe acute respiratory syndrome coronavirus (SARS-CoV) is a newly emergent virus responsible for a worldwide epidemic in 2003. The coronavirus …
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Elucidation of the stability and functional regions of the human coronavirus OC43 nucleocapsid protein
2009 / Protein Science
Human coronavirus OC43 (HCoV‐OC43) is one of the causes of the “common cold” in human during seasons of cold weather. …
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Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core
2006 / Journal of Structural Biology
The Spike (S) protein of SARS-coronavirus (SARS-CoV) mediates viral entry into host cells. It contains two heptad repeat regions, denoted HRN and HRC. We …
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Reversible Unfolding of the Severe Acute Respiratory Syndrome Coronavirus Main Protease in Guanidinium Chloride
2007 / Biophysical Journal
Chemical denaturant sensitivity of the dimeric main protease from severe acute respiratory syndrome (SARS) coronavirus to guanidinium chloride was examined in terms of fluorescence spectroscopy, circular …
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Biochemical and immunological studies of nucleocapsid proteins of severe acute respiratory syndrome and 229E human coronaviruses
2005 / Proteomics
Severe acute respiratory syndrome (SARS) is a serious health threat and its early diagnosis is important for infection control and …
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Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase N Terminus Is Indispensable for Proteolytic Activity but Not for Enzyme Dimerization
2004 / Journal of Biological Chemistry
Severe acute respiratory syndrome (SARS) coronavirus is a novel human coronavirus and is responsible for SARS infection. SARS coronavirus 3C-like …
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Structural Characterization of the SARS-Coronavirus Spike S Fusion Protein Core
2004 / Journal of Biological Chemistry
The spike (S) glycoprotein of coronaviruses mediates viral entry into host cells. It is a type 1 viral fusion protein …
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Mutation of Glu-166 Blocks the Substrate-Induced Dimerization of SARS Coronavirus Main Protease
2010 / Biophysical Journal
The maturation of SARS coronavirus involves the autocleavage of polyproteins 1a and 1ab by the main protease (Mpro) and a papain-like protease; these represent …
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Quaternary Structure of the Severe Acute Respiratory Syndrome (SARS) Coronavirus Main Protease
2004 / Biochemistry
SARS (severe acute respiratory syndrome) has been one of the most severe viral infectious diseases last year and still remains …
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Differential domain structure stability of the severe acute respiratory syndrome coronavirus papain-like protease
2012 / Archives of Biochemistry and Biophysics
Papain-like protease (PLpro) from severe acute respiratory syndrome (SARS) coronavirus is one of the two proteases involved in the proteolytic processing of the virion polyproteins. In …
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Structural and functional characterization of MERS coronavirus papain-like protease
2014 / Journal of Biomedical Science
A new highly pathogenic human coronavirus (CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), has emerged in Jeddah and Saudi Arabia …
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Isolation of eudesmanes from Pluchea odorata and evaluation of their effects on cancer cell growth and tumor invasiveness in vitro
2017 / Phytochemistry
The traditionally used Central American medicinal plant Pluchea odorata, known as an anti-inflammatory and cancer cell growth-inhibiting remedy, was subjected to …
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The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex
2003 / Journal of Virology
Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S protein of the murine coronavirus mouse …
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Construct design, biophysical, and biochemical characterization of the fusion core from mouse hepatitis virus (a coronavirus) spike protein
2004 / Protein Expression and Purification
Membrane fusion between virus and host cells is the key step for enveloped virus entry and is mediated by the viral envelope fusion …
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Characterization of HCoV-229E fusion core: Implications for structure basis of coronavirus membrane fusion
2006 / Biochemical and Biophysical Research Communications
Human coronavirus 229E (HCoV-229E), a member of group I coronaviruses, has been identified as one of the major viral agents causing respiratory …
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Biochemical and biophysical characterization of the transmissible gastroenteritis coronavirus fusion core
2005 / Biochemical and Biophysical Research Communications
Transmissible gastroenteritis coronavirus (TGEV) is one of the most destructive agents, responsible for the enteric infections that are lethal for suckling …
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Role of phosphorylation clusters in the biology of the coronavirus infectious bronchitis virus nucleocapsid protein
2008 / Virology
The coronavirus infectious bronchitis virus (IBV) nucleocapsid (N) protein is an RNA binding protein which is phosphorylated at two conserved clusters. Kinetic analysis of RNA binding indicated that the C-terminal phosphorylation cluster …
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The Aromatic Domain of the Coronavirus Class I Viral Fusion Protein Induces Membrane Permeabilization: Putative Role during Viral Entry
2004 / Biochemistry
Coronavirus (CoV) entry is mediated by the viral spike (S) glycoprotein, a class I viral fusion protein. During viral and …
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Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein
2006 / Viral Research
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is the cause of an atypical pneumonia that affected Asia, North America and Europe …
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